Iquique se encuentra a 1726 kilómetros de Valparaíso. La duración del viaje en promedio es de 25 horas, en categoría semi cama o cama dependiendo de la compañía de buses, las que atraviesan la Ruta 5 Norte que conecta ambas ciudades.
Los buses salen desde Iquique del Terminal de Buses de Iquique o terminales/paraderos definidos por cada empresa. En Valparaíso llegan al Terminal Rodoviario de Valparaíso.
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Iquique is a city of the first Region of Tarapacá being one of the northern cities known for the beauty of its beaches and its coastal desert climate that simulates an eternal summer. From Iquique you can visit the Pica Oasis, famous for its agricultural products in the Atacama desert and for its wells known as "chocas", suitable for bathing. You can also visit historical sites such as the Humberstone and Santa Laura nitrate mines. Less than an hour away is the town of La Tirana, where one of the largest religious festivals in Chile takes place around La Virgen del Carmen. The obligatory visit is to the ZOFRI, free zone where you can find multiple products free of taxes. There are many hotels in Iquique, among which the Hotel Diego de Almagro and the Hotel Terrado stand out.
Valparaíso is one of the largest cities in the country. It is the main port of the country and center of legislative power since the congress is located in its central area, just a few steps from the bus terminal of the city. It is characterized by its countless hills and viewpoints of the port, with its traditional elevators and funiculars, offering multiple options of walks to its visitors, among which Cerro Concepción, Paseo Gervasoni and the elevators Reina Victoria, Polanco and El Peral stand out. In the new year one of the largest pyrotechnic shows in the world is performed along its coast.